Celebrating 11 years of rallying collective intelligence to co-create sustainable societal impact

2024 Annual Report

Introduction
from the CEO Projects Partners Financial

We believe the world’s most important and complex societal issues are best solved when we address them collectively.

Nicholas Brooke
CEO & Founder The Synergist

We have learned a lot along the way. In our journey to bring this idea to fruition, we have tested and shaped, together with our partners, the approaches, beliefs and ways of working that are necessary for success. The Synergist as a backbone organization and its system for collaboration does not only convene, but also actively creates the conditions - through governance, skills and resources - for disconnected individuals, organizations and initiatives to find common ground, rally collective intelligence and collaborate to systematically build systems to deliver real impact on the ground. In 2023 we started to capture these learnings starting with a Manifesto to inspire and inform others who aspire to become system changemakers. There is still much work to be done.

This belief has been 11 years in the making. When we started tackling societal issues such as maternal health and dengue fever 11 years ago, our idea that we could bring together people from all walks of life and harness this collective expertise and momentum to actually solve the world’s most challenging societal issues was still a germinating seed in the ground, an idea to be nurtured and tested.

11 years on, our growing global community across collaborative programs in ever-expanding areas such as patient engagement, personalized healthcare, women’s health, and sustainable wellbeing have demonstrated that this vision is not only possible, it is a proven success that can be replicated and scaled to tackle other pressing societal challenges that we face today.

Our partners and collaborators in each collaborative organization have much to be proud of, and the success of these organizations is testament to the expertise, commitment and energy they each bring. Yet we at The Synergist are especially proud of the bridges and synergies we are building across these issue areas, such as the launch of the Patient Movement Catalyst, a collaboration for patient capacity building, and taking the opportunity of the Patient Engagement Open Forum to accelerate patient engagement advancements, a flourishing community of practice in personalized healthcare to improve patient outcomes, and to accelerate much needed action in the area of women-centric care and health R&D.

To learn more about how The Synergist serves as the backbone organization driving collective action and creating sustainable impact,

The Synergist organization serves as a backbone, bringing together people and institutions to tackle complex societal issues.

As an independent, neutral partner, we coordinate wide-ranging stakeholders to collaborate effectively.

However, creating lasting impact takes more than just bringing people together—it requires thoughtful investment in structuring collaborations, developing the necessary skills, and building experience. We’ve organized key elements of this approach, ensuring that our efforts are grounded in a strategic framework.

Below, we explore the cardinal points that guide our day-to-day work, showing how we complement our strong beliefs with the expertise, tools, and acumen required to transform these beliefs into real societal impact.

To achieve sustainable societal outcomes,

The Synergist follows a holistic approach that combines purpose, strategy, and ideas.

This model is built on four pillars:

Changing mindsets
by fostering collective intelligence and non-competitive environments

Running initiatives with true business acumen
through tools, systems thinking, and robust platforms

Embracing complexity
by listening, nurturing diversity, and moving from linear to non-linear thinking; and finally

Being purpose-driven
with a shared vision and altruistic commitment to creating lasting impact. These elements work together to break conventions and drive meaningful change.

The Synergist equips each organization with a comprehensive set of

tools, methodologies, and supporting functions to drive collaboration and impact.

This framework includes essential supporting functions like finance, IT, and management software, as well as dedicated tools such as patient engagement frameworks and online repositories.

Our digital network serves as a powerful platform for connecting stakeholders around critical societal issues, while proprietary methodologies ensure a structured, evidence-based approach. Central to our approach is systems thinking, which allows us to understand how the individual components work together to achieve greater societal impact.

Each organization within The Synergist is designed to

operate with a blend of dedicated resources and shared services.

As illustrated, each initiative is equipped with its own:

Financial systems

Governance

Decision-making bodies

Core team

while benefiting from shared services like HR, IT, communications, and finance. This hybrid model allows for agility, access to expertise, and economies of scale, creating efficiencies that drive sustainability and amplify the impact of each program.

From Tested to Targeted Treatments

PFMD

Motherhood Collective Impact Programme

European Funded Projects

They made all this possible

An aggregation of partners from all projects.

Financial Section

At The Synergist we believe in the causes and topics we address and work towards the end goal independent of external support and funding.

We strive to keep projects alive because of our belief in the necessity of their success, investing our resources and effort even when the support is dwindling.

PFMD

Turnover

2,923,750 €

Project Expenses

2,924,193 €

Membership fees

1,362,500 €

Specifically funded projects

1,716,250 €

From Testing to Targeted Treatments

Turnover

1,118,000 €

Project Expenses

1,118,868 €

Membership fees

858,000 €

Specifically funded projects

2024 Annual Report

We believe the world’s most important and complex societal issues are best solved when we address them collectively.

To learn more about how The Synergist serves as the backbone organization driving collective action and creating sustainable impact, click here.

The Synergist organization serves as a backbone, bringing together people and institutions to tackle complex societal issues.

As an independent, neutral partner, we coordinate wide-ranging stakeholders to collaborate effectively.

To achieve sustainable societal outcomes,

The Synergist follows a holistic approach that combines purpose, strategy, and ideas.

This model is built on four pillars:

Changing mindsets by fostering collective intelligence and non-competitive environments

Running initiatives with true business acumen through tools, systems thinking, and robust platforms

Embracing complexity by listening, nurturing diversity, and moving from linear to non-linear thinking; and finally

Being purpose-driven with a shared vision and altruistic commitment to creating lasting impact. These elements work together to break conventions and drive meaningful change.

The Synergist equips each organization with a comprehensive set of

tools, methodologies, and supporting functions to drive collaboration and impact.

This framework includes essential supporting functions like finance, IT, and management software, as well as dedicated tools such as patient engagement frameworks and online repositories.

Each organization within The Synergist is designed to

operate with a blend of dedicated resources and shared services.

As illustrated, each initiative is equipped with its own:

From Tested to Targeted Treatments

PFMD

Motherhood Collective Impact Programme

European Funded Projects

They made all this possible

An aggregation of partners from all projects.

Financial Section

At The Synergist we believe in the causes and topics we address and work towards the end goal independent of external support and funding.

PFMD

From Testing to Targeted Treatments

Patient Movement Catalyst

GUIDE.MRD

Conception

Gravitate

EU-PEARL

Other

To learn more about how The Synergist serves as the backbone organization driving collective action and creating sustainable impact,

Changing mindsets
by fostering collective intelligence and non-competitive environments

Running initiatives with true business acumen
through tools, systems thinking, and robust platforms

Embracing complexity
by listening, nurturing diversity, and moving from linear to non-linear thinking; and finally

Being purpose-driven
with a shared vision and altruistic commitment to creating lasting impact. These elements work together to break conventions and drive meaningful change.